Mixed Connective Tissue Disease (Sharp's Syndrome) - Symptoms, Causes, and Doctors- My Mediland

About- Mixed connective tissue disease also known as sharp's syndrome, is an autoimmune disease characterized by the existence of high blood levels of a specific autoantibody (anti-U1 ribonucleoprotein, RNP). It’s sometimes called an overlap disease because many of its symptoms overlap with those of other connective tissue disorders, such as lupus, polymyositis, and scleroderma.

Symptoms-

Acid reflux

Chest pain

Fatigue

Fever

Hardening or tightening patches of skin

Malaise

Muscle and joint pain

Muscle weakness

Pain in multiple joints

Raynaud's disease

Shortness of breath

Skin rash

Stomach inflammation

Swollen fingers or hands

Swollen joints

Causes-
The exact cause of Mixed connective tissue disease is not properly understood.

Specialists to visit-
Dermatologist
Immunologist
Rheumatologist

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References
https://en.wikipedia.org
https://www.mayoclinic.org
https://www.healthline.com
https://emedicine.medscape.com
https://www.msdmanuals.com